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A European, multicentre, retrospective, non-interventional study (EU-TREAT) of the effectiveness of insulin degludec after switching basal insulin in a population with type 1 or type 2 diabetes.


ABSTRACT: AIMS:To evaluate the clinical effectiveness of switching to insulin degludec (IDeg) in insulin-treated patients with either type 1 diabetes (T1DM) or type 2 diabetes (T2DM) under conditions of routine clinical care. MATERIALS AND METHODS:This was a multicentre, retrospective, chart review study. In all patients, basal insulin was switched to IDeg at least 6?months before the start of data collection. Baseline was defined as the most recent recording during the 3-month period before first prescription of IDeg. Values are presented as mean [95%CI]. RESULTS:T1DM (n?=?1717): HbA1c decreased by -2.2 [-2.6; -2.0] mmol/mol (-0.20 [-0.24; -0.17]%) at 6?months vs baseline (P?

SUBMITTER: Siegmund T 

PROVIDER: S-EPMC5836866 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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A European, multicentre, retrospective, non-interventional study (EU-TREAT) of the effectiveness of insulin degludec after switching basal insulin in a population with type 1 or type 2 diabetes.

Siegmund Thorsten T   Tentolouris Nikolaos N   Knudsen Søren T ST   Lapolla Annunziata A   Prager Rudolf R   Phan Tra-Mi TM   Wolden Michael L ML   Schultes Bernd B  

Diabetes, obesity & metabolism 20171121 3


<h4>Aims</h4>To evaluate the clinical effectiveness of switching to insulin degludec (IDeg) in insulin-treated patients with either type 1 diabetes (T1DM) or type 2 diabetes (T2DM) under conditions of routine clinical care.<h4>Materials and methods</h4>This was a multicentre, retrospective, chart review study. In all patients, basal insulin was switched to IDeg at least 6 months before the start of data collection. Baseline was defined as the most recent recording during the 3-month period befor  ...[more]

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