Prevalence of autosomal dominant polycystic kidney disease in the European Union.

ABSTRACT:

Background

Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end-stage renal disease, but estimates of its prevalence vary by >10-fold. The objective of this study was to examine the public health impact of ADPKD in the European Union (EU) by estimating minimum prevalence (point prevalence of known cases) and screening prevalence (minimum prevalence plus cases expected after population-based screening).

Methods

A review of the epidemiology literature from January 1980 to February 2015 identified population-based studies that met criteria for methodological quality. These examined large German and British populations, providing direct estimates of minimum prevalence and screening prevalence. In a second approach, patients from the 2012 European Renal

SUBMITTER: Willey CJ 

PROVIDER: S-EPMC5837385 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature