Ontology highlight
ABSTRACT:
SUBMITTER: Palla AR
PROVIDER: S-EPMC5840183 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Palla Amruth R AR Doll Donald D
ImmunoTargets and therapy 20180302
Merkel cell carcinoma (MCC), a rare skin cancer, is associated with high mortality, especially in a metastatic setting. Though conventional chemotherapy with platinum and etoposide has had high response rates, many of the patients have had early relapse without any effective therapy thereafter. Recently, immune check point inhibitors have shown very good durable responses, leading to the approval of a programmed death-ligand 1 inhibitor Avelumab for these patients. We briefly review the epidemio ...[more]