Clinical significance of microRNA-449a in hepatocellular carcinoma with microarray data mining together with initial bioinformatics analysis.
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ABSTRACT:
SUBMITTER: Yang X
PROVIDER: S-EPMC5841030 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
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Clinical significance of microRNA-449a in hepatocellular carcinoma with microarray data mining together with initial bioinformatics analysis.
Yang Xia X Wang Han-Lin HL Liang Hai-Wei HW Liang Liang L Wen Dong-Yue DY Zhang Rui R Chen Gang G Wei Dan-Ming DM
Experimental and therapeutic medicine 20180205 4
Increasing evidence has demonstrated that microRNA (miR)-449a expression is reduced in various types of tumors and that it serves as a tumor suppressor. However, the molecular mechanism of miR-449a in hepatocellular carcinoma (HCC) has not been thoroughly elucidated and is disputed. Therefore, the aim of the present work was to systematically review the current literature and to utilize the public Gene Expression Omnibus database to determine the role of miR-449a and its significance in HCC. A t ...[more]
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