Ontology highlight
ABSTRACT:
SUBMITTER: Kazerounian S
PROVIDER: S-EPMC5842194 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Kazerounian Shideh S Lawler Jack J
Journal of cell communication and signaling 20171220 1
Angiogenesis or neovascularization is a complex multi-step physiological process that occurs throughout life both in normal tissues and in disease. It is tightly regulated by the balance between pro-angiogenic and anti-angiogenic factors. The angiogenic switch has been identified as the key step during tumor progression in which the balance between pro-angiogenic and anti-angiogenic factors leans toward pro-angiogenic stimuli promoting the progression of tumors from dormancy to dysplasia and ult ...[more]