Ontology highlight
ABSTRACT:
SUBMITTER: Qi ZH
PROVIDER: S-EPMC5843398 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Qi Zi-Hao ZH Xu Hua-Xiang HX Zhang Shi-Rong SR Xu Jin-Zhi JZ Li Shuo S Gao He-Li HL Jin Wei W Wang Wen-Quan WQ Wu Chun-Tao CT Ni Quan-Xing QX Yu Xian-Jun XJ Liu Liang L
International journal of oncology 20180207 4
Pancreatic cancer is a lethal disease with a high metastatic potential. In our previous study, we identified a specific subgroup of patients with pancreatic cancer with a serum signature of carcinoembryonic antigen (CEA)+/cancer antigen (CA)125+/CA19-9 ≥1,000 U/ml. In this study, by using high-throughput screening analysis, we found that receptor-interacting protein kinases 4 (RIPK4) may be a key molecule involved in the high metastatic potential of this subgroup of patients with pancreatic canc ...[more]