Ontology highlight
ABSTRACT:
SUBMITTER: Park K
PROVIDER: S-EPMC5843474 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20170510 20
Binuclear non-heme iron enzymes activate O<sub>2</sub> for diverse chemistries that include oxygenation of organic substrates and hydrogen atom abstraction. This process often involves the formation of peroxo-bridged biferric intermediates, only some of which can perform electrophilic reactions. To elucidate the geometric and electronic structural requirements to activate peroxo reactivity, the active peroxo intermediate in 4-aminobenzoate N-oxygenase (AurF) has been characterized spectroscopica ...[more]