Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez C
PROVIDER: S-EPMC5843601 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Rodriguez Christophe C Soulier Alexandre A Demontant Vanessa V Poiteau Lila L Mercier-Darty Mélanie M Bouvier-Alias Magali M Pawlotsky Jean-Michel JM Chevaliez Stéphane S
Scientific reports 20180308 1
Hepatitis C virus (HCV) genotype and subtype (1a/1b) identification is needed to tailor anti-HCV therapy. Currently available methods accurately identify the genotype and differentiate subtypes 1a from 1b. However, these assays have not been designed to identify other HCV subtypes, nor to recognize mixed genotype/subtype infections, emphasizing the need for a high-resolution system based on phylogenetic analysis of reads obtained by deep sequencing of a relevant genome region. The aim of this st ...[more]