Ontology highlight
ABSTRACT:
SUBMITTER: de Almeida JRF
PROVIDER: S-EPMC5843658 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
de Almeida José Roberto Fogaça JRF Jannuzzi Grasielle Pereira GP Kaihami Gilberto Hideo GH Breda Leandro Carvalho Dantas LCD Ferreira Karen Spadari KS de Almeida Sandro Rogério SR
Scientific reports 20180308 1
Sporothrix brasiliensis is the most virulent fungus of the Sporothrix complex and is the main species recovered in the sporotrichosis zoonotic hyperendemic area in Rio de Janeiro. A vaccine against S. brasiliensis could improve the current sporotrichosis situation. Here, we show 3 peptides from S. brasiliensis immunogenic proteins that have a higher likelihood for engaging MHC-class II molecules. We investigated the efficiency of the peptides as vaccines for preventing subcutaneous sporotrichosi ...[more]