Ontology highlight
ABSTRACT:
SUBMITTER: Hu-Lieskovan S
PROVIDER: S-EPMC5844278 | biostudies-literature | 2017 Jan/Feb
REPOSITORIES: biostudies-literature
Hu-Lieskovan Siwen S Ribas Antoni A
Cancer journal (Sudbury, Mass.) 20170101 1
The discovery of immune checkpoints and subsequent clinical development of checkpoint inhibitors have revolutionized the field of oncology. The durability of the antitumor immune responses has raised the hope for long-term patient survival and potential cure; however, currently, only a minority of patients respond. Combination strategies to help increase antigen release and T-cell priming, promote T-cell activation and homing, and improve the tumor immune microenvironment, all guided by predicti ...[more]