Chemically Defined Antibody- and Small Molecule-Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis.
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ABSTRACT: We present the first direct comparative evaluation of an antibody-drug conjugate and of a small molecule-drug conjugate for cancer therapy, using chemically defined products which bind with high-affinity to carbonic anhydrase IX, a marker of tumor hypoxia and of renal cell carcinoma.
SUBMITTER: Cazzamalli S
PROVIDER: S-EPMC5844464 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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