Sleeve gastrectomy surgery: when 2 alcoholic drinks are converted to 4.

ABSTRACT: BACKGROUND:While it is well established that Roux-en-Y gastric bypass (RYGB) causes a rapid and heightened peak blood alcohol concentration (BAC), results from previous studies on the effects of sleeve gastrectomy (SG) on alcohol pharmacokinetics are conflicting. Data from 2 studies found SG did not affect BAC, whereas another study found SG caused a heightened peak BAC after alcohol ingestion. Moreover, these 3 studies estimated BAC from breathalyzers, which might not reliably estimate peak BAC. OBJECTIVES:The aims of this study were to evaluate (1) the effect of SG, relative to RYGB and a presurgery group, on alcohol pharmacokinetics and subjective effects, and (2) whether breathalyzers are reliable in this population. SETTING:Single-center prospective nonrandomized trial. METHODS:We per

SUBMITTER: Acevedo MB 

PROVIDER: S-EPMC5844810 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature