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Polygonumins A, a newly isolated compound from the stem of Polygonum minus Huds with potential medicinal activities.


ABSTRACT: Polygonumins A, a new compound, was isolated from the stem of Polygonum minus. Based on NMR results, the compound's structure is identical to that of vanicoside A, comprising four phenylpropanoid ester units and a sucrose unit. The structure differences were located at C-3??'. The cytotoxic activity of polygonumins A was evaluated on several cancer cell lines by a cell viability assay using tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). The compound showed the highest antiproliferative (p?

SUBMITTER: Ahmad R 

PROVIDER: S-EPMC5845017 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Polygonumins A, a newly isolated compound from the stem of Polygonum minus Huds with potential medicinal activities.

Ahmad Rafidah R   Sahidin I I   Taher Muhammad M   Low ChenFei C   Noor Normah Mohd NM   Sillapachaiyaporn Chanin C   Chuchawankul Siriporn S   Sarachana Tewarit T   Tencomnao Tewin T   Iskandar Faizah F   Rajab Nor Fadilah NF   Baharum Syarul Nataqain SN  

Scientific reports 20180309 1


Polygonumins A, a new compound, was isolated from the stem of Polygonum minus. Based on NMR results, the compound's structure is identical to that of vanicoside A, comprising four phenylpropanoid ester units and a sucrose unit. The structure differences were located at C-3″″'. The cytotoxic activity of polygonumins A was evaluated on several cancer cell lines by a cell viability assay using tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). The compound showed th  ...[more]

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