Ontology highlight
ABSTRACT:
SUBMITTER: Ceccarelli S
PROVIDER: S-EPMC5845512 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ceccarelli Simona S Nodale Cristina C Vescarelli Enrica E Pontecorvi Paola P Manganelli Valeria V Casella Giovanni G Onesti Maria Giuseppina MG Sorice Maurizio M Romano Ferdinando F Angeloni Antonio A Marchese Cinzia C
Stem cells international 20180225
Adipogenesis is regulated by a complex network of molecules, including fibroblast growth factors. Keratinocyte growth factor (KGF) has been previously reported to promote proliferation on rat preadipocytes, although the expression of its specific receptor, FGFR2-IIIb/KGFR, is not actually detected in mesenchymal cells. Here, we demonstrate that human adipose-derived stem cells (ASCs) show increased expression of KGF during adipogenic differentiation, especially in the early steps. Moreover, KGF ...[more]