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Epidemiologic analysis of respiratory viral infections among Singapore military servicemen in 2016.

ABSTRACT: Respiratory illnesses have been identified as a significant factor leading to lost training time and morbidity among Singapore military recruits. A surveillance programme has been put in place to determine etiological agents responsible for febrile, as well as afebrile respiratory illnesses in a military camp. The goal of the study is to better understand the epidemiology of these diseases and identify potential countermeasures to protect military recruits against them.From Jan 2016 - Jan 2017, a total of 2647 respiratory cases were enrolled into the surveillance programme. The cases were further stratified into Febrile Respiratory Illness (FRI, with body temperature?>?37.5 °C) or Acute Respiratory Illness (ARI, with body temperature?

SUBMITTER: Lau YF

PROVIDER: S-EPMC5848554 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Epidemiologic analysis of respiratory viral infections among Singapore military servicemen in 2016.

Lau Yuk-Fai YF Koh Wee-Hong Victor WV Kan Clement C Dua Poh-Choo Alethea PA Lim Ai-Sim Elizabeth AE Liaw Chin-Wen Jasper CJ Gao Qiu-Han QH Chng Jeremiah J Lee Vernon J VJ Tan Boon-Huan BH Loh Jin-Phang JP

BMC infectious diseases 20180312 1

<h4>Background</h4>Respiratory illnesses have been identified as a significant factor leading to lost training time and morbidity among Singapore military recruits. A surveillance programme has been put in place to determine etiological agents responsible for febrile, as well as afebrile respiratory illnesses in a military camp. The goal of the study is to better understand the epidemiology of these diseases and identify potential countermeasures to protect military recruits against them.<h4>Met ...[more]

PMID: 29529993

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Project description:With the global over 60-year-old population predicted to more than double over the next 35 years, caring for this aging population has become a major global healthcare challenge. In 2016 there were over 1 million deaths in >70 year olds due to lower respiratory tract infections; 13-31% of these have been reported to be caused by viruses. Since then, there has been a global COVID-19 pandemic, which has caused over 2.3 million deaths so far; increased age has been shown to be the biggest risk factor for morbidity and mortality. Thus, the burden of respiratory viral infections in the elderly is becoming an increasing unmet clinical need. Particular challenges are faced due to the interplay of a variety of factors including complex multimorbidities, decreased physiological reserve and an aging immune system. Moreover, their atypical presentation of symptoms may lead to delayed necessary care, prescription of additional drugs and prolonged hospital stay. This leads to morbidity and mortality and further nosocomial spread. Clinicians currently have limited access to sensitive detection methods. Furthermore, a lack of effective antiviral treatments means there is little incentive to diagnose and record specific non-COVID-19 viral infections. To meet this unmet clinical need, it is first essential to fully understand the burden of respiratory viruses in the elderly. Doing this through prospective screening research studies for all respiratory viruses will help guide preventative policies and clinical trials for emerging therapeutics. The implementation of multiplex point-of-care diagnostics as a mainstay in all healthcare settings will be essential to understand the burden of respiratory viruses, diagnose patients and monitor outbreaks. The further development of novel targeted vaccinations as well as anti-viral therapeutics and new ways to augment the aging immune system is now also essential.The reviews of this paper are available via the supplemental material section.

Dataset Information

Epidemiologic analysis of respiratory viral infections among Singapore military servicemen in 2016.

Publications

Epidemiologic analysis of respiratory viral infections among Singapore military servicemen in 2016.

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