Ontology highlight
ABSTRACT:
SUBMITTER: Simonian M
PROVIDER: S-EPMC5849118 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Simonian Miganoosh M Mosallayi Meysam M Miraghajani Maryam M Feizi Awat A Khosravi Sharifeh S Salehi Ahmad Reza AR Mortazavi Deniz D Saberi Farideh F Salehi Rasoul R
Gastroenterology and hepatology from bed to bench 20180101 1
<h4>Aim</h4>In present study we have elucidated the role of 2758 A>G (rs696), in the recognition site of miR449a in the 3' UTR of NFKB inhibitor alpha (NFKBIA) gene, in development of sporadic colorectal cancer.<h4>Background</h4>Colorectal cancer (CRC) is rated as second cause of cancer death. Genetic determinants are considered as driving forces in development of sporadic CRC. Single nucleotide polymorphisms (SNPs), are attributed as the main genetic factor in cancers susceptibility. MicroRNAs ...[more]