Ontology highlight
ABSTRACT:
SUBMITTER: Brendel M
PROVIDER: S-EPMC5849231 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
European journal of nuclear medicine and molecular imaging 20150129 5
<h4>Purpose</h4>Late-life depression even in subsyndromal stages is strongly associated with Alzheimer's disease (AD). Furthermore, brain amyloidosis is an early biomarker in subjects who subsequently suffer from AD and can be sensitively detected by amyloid PET. Therefore, we aimed to compare amyloid load and glucose metabolism in subsyndromally depressed subjects with mild cognitive impairment (MCI).<h4>Methods</h4>[(18)F]AV45 PET, [(18)F]FDG PET and MRI were performed in 371 MCI subjects from ...[more]