Ontology highlight
ABSTRACT:
SUBMITTER: Seale AC
PROVIDER: S-EPMC5849940 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Seale Anna C AC Bianchi-Jassir Fiorella F Russell Neal J NJ Kohli-Lynch Maya M Tann Cally J CJ Hall Jenny J Madrid Lola L Blencowe Hannah H Cousens Simon S Baker Carol J CJ Bartlett Linda L Cutland Clare C Gravett Michael G MG Heath Paul T PT Ip Margaret M Le Doare Kirsty K Madhi Shabir A SA Rubens Craig E CE Saha Samir K SK Schrag Stephanie J SJ Sobanjo-Ter Meulen Ajoke A Vekemans Johan J Lawn Joy E JE
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20171101 suppl_2
<h4>Background</h4>We aimed to provide the first comprehensive estimates of the burden of group B Streptococcus (GBS), including invasive disease in pregnant and postpartum women, fetal infection/stillbirth, and infants. Intrapartum antibiotic prophylaxis is the current mainstay of prevention, reducing early-onset infant disease in high-income contexts. Maternal GBS vaccines are in development.<h4>Methods</h4>For 2015 live births, we used a compartmental model to estimate (1) exposure to materna ...[more]