Management of Latent Tuberculosis Infection Among Healthcare Workers: 10-Year Experience at a Single Center.

ABSTRACT:

Background

The risk of infection with Mycobacterium tuberculosis among healthcare workers (HCWs) is estimated to be higher than the general population. However, HCW acceptance and compliance with available latent tuberculosis infection (LTBI) treatment regimens has been problematic. Recently, regimens have become available that might improve HCW acceptance and compliance with LTBI treatment.

Methods

A retrospective single-center review of Employee Health and Wellness Services records of all HCWs diagnosed with LTBI was conducted. HCWs diagnosed with LTBI were offered 9-month isoniazid (INH), 4-month rifampin (RIF), weekly rifapentine/isoniazid (RPT/INH) for 12 weeks, or no treatment. Acceptance, completion rates, and side effects were reported for each regimen. Comparisons o

SUBMITTER: Arguello Perez E 

PROVIDER: S-EPMC5850550 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature