Gene Tree Discordance Does Not Explain Away the Temporal Decline of Convergence in Mammalian Protein Sequence Evolution.
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ABSTRACT:
SUBMITTER: Zou Z
PROVIDER: S-EPMC5850593 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Gene Tree Discordance Does Not Explain Away the Temporal Decline of Convergence in Mammalian Protein Sequence Evolution.
Zou Zhengting Z Zhang Jianzhi J
Molecular biology and evolution 20170701 7
Several authors reported lower frequencies of protein sequence convergence between more distantly related evolutionary lineages and attributed this trend to epistasis, which renders the acceptable amino acids at a site more different and convergence less likely in more divergent lineages. A recent primate study, however, suggested that this trend is at least partially and potentially entirely an artifact of gene tree discordance (GTD). Here, we demonstrate in a genome-wide data set from 17 mamma ...[more]
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