Inferring Past Environments from Ancient Epigenomes.
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ABSTRACT:
SUBMITTER: Gokhman D
PROVIDER: S-EPMC5850778 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Inferring Past Environments from Ancient Epigenomes.
Gokhman David D Malul Anat A Carmel Liran L
Molecular biology and evolution 20171001 10
Analyzing the conditions in which past individuals lived is key to understanding the environments and cultural transitions to which humans had to adapt. Here, we suggest a methodology to probe into past environments, using reconstructed premortem DNA methylation maps of ancient individuals. We review a large body of research showing that differential DNA methylation is associated with changes in various external and internal factors, and propose that loci whose DNA methylation level is environme ...[more]
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