Ontology highlight
ABSTRACT:
SUBMITTER: Porath HT
PROVIDER: S-EPMC5850803 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Porath Hagit T HT Schaffer Amos A AA Kaniewska Paulina P Alon Shahar S Eisenberg Eli E Rosenthal Joshua J Levanon Erez Y EY Levy Oren O
Molecular biology and evolution 20170801 8
The highly conserved ADAR enzymes, found in all multicellular metazoans, catalyze the editing of mRNA transcripts by the deamination of adenosines to inosines. This type of editing has two general outcomes: site specific editing, which frequently leads to recoding, and clustered editing, which is usually found in transcribed genomic repeats. Here, for the first time, we looked for both editing of isolated sites and clustered, non-specific sites in a basal metazoan, the coral Acropora millepora d ...[more]