Ontology highlight
ABSTRACT:
SUBMITTER: Lai HM
PROVIDER: S-EPMC5852003 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Nature communications 20180314 1
Modern clearing techniques for the three-dimensional (3D) visualisation of neural tissue microstructure have been very effective when used on rodent brain but very few studies have utilised them on human brain material, mainly due to the inherent difficulties in processing post-mortem tissue. Here we develop a tissue clearing solution, OPTIClear, optimised for fresh and archival human brain tissue, including formalin-fixed paraffin-embedded material. In light of practical challenges with immunos ...[more]