Comparative roles of clpA and clpB in the survival of S. Typhimurium under stress and virulence in poultry.
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ABSTRACT:
SUBMITTER: Sangpuii L
PROVIDER: S-EPMC5852057 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
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Comparative roles of clpA and clpB in the survival of S. Typhimurium under stress and virulence in poultry.
Sangpuii Lal L Dixit Sunil Kumar SK Kumawat Manoj M Apoorva Shekhar S Kumar Mukesh M Kappala Deepthi D Goswami Tapas Kumar TK Mahawar Manish M
Scientific reports 20180314 1
By assisting in the proteolysis, disaggregation and refolding of the aggregated proteins, Caseinolytic proteases (Clps) enhance the cellular survival under stress conditions. In the current study, comparative roles of two such Clps, ClpA (involved in proteolysis) and ClpB (involved in protein disaggregation and refolding) in the survival of Salmonella Typhimurium (S. Typhimurium) under different stresses and in virulence have been investigated. clpA and clpB gene deletion mutant strains (∆clpA a ...[more]
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