Ontology highlight
ABSTRACT:
SUBMITTER: Du J
PROVIDER: S-EPMC5852707 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Du Jingjing J Shen Linyuan L Tan Zhendong Z Zhang Peiwen P Zhao Xue X Xu Yan Y Gan Mailing M Yang Qiong Q Ma Jideng J Jiang An'an A Tang Guoqing G Jiang Yanzhi Y Jin Long L Li Mingzhou M Bai Lin L Li Xuewei X Wang Jinyong J Zhang Shunhua S Zhu Li L
Nutrients 20180126 2
Obesity is a major driver of metabolic diseases such as nonalcoholic fatty liver disease, certain cancers, and insulin resistance. However, there are no effective drugs to treat obesity. Betaine is a nontoxic, chemically stable and naturally occurring molecule. This study shows that dietary betaine supplementation significantly inhibits the white fat production in a high-fat diet (HFD)-induced obese mice. This might be due to betaine preventing the formation of new white fat (WAT), and guiding t ...[more]