Ontology highlight
ABSTRACT:
SUBMITTER: George V
PROVIDER: S-EPMC5853564 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
George Varghese V Harrison Linda L Roach Margaret M Li Xiao-Dong XD Tierney Camlin C Fischl Margaret A MA Aberg Judith J Tebas Pablo P Asmuth David M DM Pollard Richard B RB Godfrey Catherine C Pahwa Savita S
The Journal of infectious diseases 20171101 9
A nested case-cohort study was performed in participants of a clinical trial of first-line human immunodeficiency virus treatments to investigate plasma biomarkers of inflammation and microbial translocation for their association with immune reconstitution inflammatory syndrome (IRIS). Fifty-one of 1452 participants with baseline CD4 count <350 cells/μL developed IRIS. Plasma from 51 IRIS cases, including 6 stratified by preenrollment CD4 count ≤200 cells/μL, were analyzed and compared to 94 non ...[more]