Ontology highlight
ABSTRACT:
SUBMITTER: Charles RC
PROVIDER: S-EPMC5853614 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Charles Richelle C RC Nakajima Rie R Liang Li L Jasinskas Al A Berger Amanda A Leung Daniel T DT Kelly Meagan M Xu Peng P Kovác Pavol P Giffen Samantha R SR Harbison James D JD Chowdhury Fahima F Khan Ashraful I AI Calderwood Stephen B SB Bhuiyan Taufiqur Rahman TR Harris Jason B JB Felgner Philip L PL Qadri Firdausi F Ryan Edward T ET
The Journal of infectious diseases 20170701 1
<h4>Background</h4>Cholera is a severe dehydrating illness of humans caused by toxigenic strains of Vibrio cholerae O1 or O139. Identification of immunogenic V. cholerae antigens could lead to a better understanding of protective immunity in human cholera.<h4>Methods</h4>We probed microarrays containing 3652 V. cholerae antigens with plasma and antibody-in-lymphocyte supernatant (ALS, a surrogate marker of mucosal immune responses) from patients with severe cholera caused by V. cholerae O1 in Ba ...[more]