Ontology highlight
ABSTRACT:
SUBMITTER: Levine MZ
PROVIDER: S-EPMC5853660 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
The Journal of infectious diseases 20170901 suppl_4
Recently, novel highly pathogenic avian influenza H5Nx viruses (clade 2.3.4.4) caused outbreaks in US poultry. We evaluated the potential of a stockpiled A(H5N1) A/Anhui/1/2005 (clade 2.3.4) vaccine to elicit cross-reactive antibody responses to these emerging viruses. Sera from subjects who received 2 doses of MF59-adjuvanted A/Anhui/1/2005, or 1 dose of MF59-adjuvanted A/Anhui/1/2005 following priming with a clade 1 vaccine were characterized by microneutralization assays and modified hemagglu ...[more]