Ontology highlight
ABSTRACT:
SUBMITTER: Moodie Z
PROVIDER: S-EPMC5854020 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Moodie Zoe Z Juraska Michal M Huang Ying Y Zhuang Yingying Y Fong Youyi Y Carpp Lindsay N LN Self Steven G SG Chambonneau Laurent L Small Robert R Jackson Nicholas N Noriega Fernando F Gilbert Peter B PB
The Journal of infectious diseases 20180201 5
<h4>Background</h4>In the CYD14 and CYD15 Phase 3 trials of the CYD-TDV dengue vaccine, estimated vaccine efficacy (VE) against symptomatic, virologically confirmed dengue (VCD) occurring between months 13 and 25 was 56.5% and 60.8%, respectively.<h4>Methods</h4>Neutralizing antibody titers to the 4 dengue serotypes in the CYD-TDV vaccine insert were measured at month 13 in a randomly sampled immunogenicity subcohort and in all VCD cases through month 25 (2848 vaccine, 1574 placebo) and studied ...[more]