Ontology highlight
ABSTRACT:
SUBMITTER: Streng ML
PROVIDER: S-EPMC5854574 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Streng Martha L ML Popa Laurentiu S LS Ebner Timothy J TJ
Nature communications 20180315 1
It is hypothesized that the cerebellum implements a forward internal model that transforms motor commands into predictions about upcoming movements. The predictions are compared with sensory feedback to generate sensory prediction errors critical to controlling movements. The simple spike firing of cerebellar Purkinje cells both lead and lag movement consistent with representations of motor predictions and sensory feedback. This study tests whether this leading and lagging modulation provides th ...[more]