Ontology highlight
ABSTRACT:
SUBMITTER: Tian KW
PROVIDER: S-EPMC5854598 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Tian Ke-Wei KW Zhang Yuan-Yuan YY Jiang Hong H Han Shu S
Scientific reports 20180315 1
The placenta has emerged as an attractive source of mesenchymal stem cells (MSCs) because of the absence of ethical issues, non-invasive access, and abundant yield. However, inflammatory cell invasion into grafts negatively impacts the survival and efficacy of transplanted cells. Previous studies have shown that synthetic C16 peptide can competitively block the transmigration of leukocytes into the central nerve system, while angiopoietin-1 (Ang-1) can inhibit inflammation-induced blood vessel l ...[more]