Ontology highlight
ABSTRACT:
SUBMITTER: Chen H
PROVIDER: S-EPMC5854957 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Chen Han H Cade Brian E BE Gleason Kevin J KJ Bjonnes Andrew C AC Stilp Adrienne M AM Sofer Tamar T Conomos Matthew P MP Ancoli-Israel Sonia S Arens Raanan R Azarbarzin Ali A Bell Graeme I GI Below Jennifer E JE Chun Sung S Evans Daniel S DS Ewert Ralf R Frazier-Wood Alexis C AC Gharib Sina A SA Haba-Rubio José J Hagen Erika W EW Heinzer Raphael R Hillman David R DR Johnson W Craig WC Kutalik Zoltan Z Lane Jacqueline M JM Larkin Emma K EK Lee Seung Ku SK Liang Jingjing J Loredo Jose S JS Mukherjee Sutapa S Palmer Lyle J LJ Papanicolaou George J GJ Penzel Thomas T Peppard Paul E PE Post Wendy S WS Ramos Alberto R AR Rice Ken K Rotter Jerome I JI Sands Scott A SA Shah Neomi A NA Shin Chol C Stone Katie L KL Stubbe Beate B Sul Jae Hoon JH Tafti Mehdi M Taylor Kent D KD Teumer Alexander A Thornton Timothy A TA Tranah Gregory J GJ Wang Chaolong C Wang Heming H Warby Simon C SC Wellman D Andrew DA Zee Phyllis C PC Hanis Craig L CL Laurie Cathy C CC Gottlieb Daniel J DJ Patel Sanjay R SR Zhu Xiaofeng X Sunyaev Shamil R SR Saxena Richa R Lin Xihong X Redline Susan S
American journal of respiratory cell and molecular biology 20180301 3
Obstructive sleep apnea (OSA) is a common heritable disorder displaying marked sexual dimorphism in disease prevalence and progression. Previous genetic association studies have identified a few genetic loci associated with OSA and related quantitative traits, but they have only focused on single ethnic groups, and a large proportion of the heritability remains unexplained. The apnea-hypopnea index (AHI) is a commonly used quantitative measure characterizing OSA severity. Because OSA differs by ...[more]