Ontology highlight
ABSTRACT:
SUBMITTER: Dey A
PROVIDER: S-EPMC5855555 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Dey Abhishek A Chakrabarti Kausik K
International journal of molecular sciences 20180124 2
Replicative capacity of a cell is strongly correlated with telomere length regulation. Aberrant lengthening or reduction in the length of telomeres can lead to health anomalies, such as cancer or premature aging. Telomerase is a master regulator for maintaining replicative potential in most eukaryotic cells. It does so by controlling telomere length at chromosome ends. Akin to cancer cells, most single-cell eukaryotic pathogens are highly proliferative and require persistent telomerase activity ...[more]