Ontology highlight
ABSTRACT:
SUBMITTER: Ruoppolo M
PROVIDER: S-EPMC5856765 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Ruoppolo Margherita M Caterino Marianna M Albano Lucia L Pecce Rita R Di Girolamo Maria Grazia MG Crisci Daniela D Costanzo Michele M Milella Luigi L Franconi Flavia F Campesi Ilaria I
Scientific reports 20180316 1
Sex differences affect several diseases and are organ-and parameter-specific. In humans and animals, sex differences also influence the metabolism and homeostasis of amino acids and fatty acids, which are linked to the onset of diseases. Thus, the use of targeted metabolite profiles in tissues represents a powerful approach to examine the intermediary metabolism and evidence for any sex differences. To clarify the sex-specific activities of liver, heart and kidney tissues, we used targeted metab ...[more]