Ontology highlight
ABSTRACT:
SUBMITTER: Khoramian Tusi B
PROVIDER: S-EPMC5857247 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Khoramian Tusi Betsabeh B Socolovsky Merav M
Experimental hematology 20180131
The advent of single-cell transcriptomics has led to the proposal of a number of novel high-resolution models for the hematopoietic system. Testing the predictions generated by such models requires cell fate potential assays of matching, single-cell resolution. Here we detail the development of an in vitro high-throughput single-cell culture assay using flow cytometrically sorted single murine bone marrow progenitors, which measures their differentiation into any of five myeloid lineages. We ide ...[more]