Impact of cumulative exposure to high-dose oral glucocorticoids on fracture risk in Denmark: a population-based case-control study.
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ABSTRACT:
SUBMITTER: Amiche MA
PROVIDER: S-EPMC5857556 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
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Impact of cumulative exposure to high-dose oral glucocorticoids on fracture risk in Denmark: a population-based case-control study.
Amiche M Amine MA Abtahi Shahab S Driessen Johanna H M JHM Vestergaard Peter P de Vries Frank F Cadarette Suzanne M SM Burden Andrea M AM
Archives of osteoporosis 20180318 1
We examined the effect of cumulative exposure to high doses of oral glucocorticoids on fracture risk. Compared to short-course users (daily dose ≥ 15 mg + cumulative < 1 g), heavy users (daily dose ≥ 15 mg + cumulative dose ≥ 1 g) had the highest risk of fracture. These patients should be monitored for fracture management strategies.<h4>Purpose</h4>The effect of cumulative exposure to high daily doses of oral glucocorticoids on fracture risk remains debated. We therefore aimed to examine the hip ...[more]
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