Ontology highlight
ABSTRACT:
SUBMITTER: Faria M
PROVIDER: S-EPMC5859099 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Faria Melissa M Fuertes Inmaculada I Prats Eva E Abad Jose Luis JL Padrós Francesc F Gomez-Canela Cristian C Casas Josefina J Estevez Jorge J Vilanova Eugenio E Piña Benjamin B Raldúa Demetrio D
Scientific reports 20180319 1
Inhibition and aging of neuropathy target esterase (NTE) by exposure to neuropathic organophosphorus compounds (OPs) can result in OP-induced delayed neuropathy (OPIDN). In the present study we aimed to build a model of OPIDN in adult zebrafish. First, inhibition and aging of zebrafish NTE activity were characterized in the brain by using the prototypic neuropathic compounds cresyl saligenin phosphate (CBDP) and diisopropylphosphorofluoridate (DFP). Our results show that, as in other animal mode ...[more]