Ontology highlight
ABSTRACT:
SUBMITTER: Tao Y
PROVIDER: S-EPMC5859247 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Tao Yiwen Y Li Pinglin P Zhang Daojing D Glukhov Evgenia E Gerwick Lena L Zhang Chen C Murray Thomas F TF Gerwick William H WH
The Journal of organic chemistry 20180308 6
Cancer cell cytotoxicity was used to guide the isolation of nine new swinholide-related compounds, named samholides A-I (1-9), from an American Samoan marine cyanobacterium cf. Phormidium sp. Their structures were determined by extensive analysis of 1D and 2D NMR spectroscopic data. The new compounds share an unusual 20-demethyl 44-membered lactone ring composed of two monomers, and they demonstrate structural diversity arising from geometric isomerization of double bonds, sugar units with uniqu ...[more]