Dataset Information
CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data.
Ontology highlight
ABSTRACT: Summary
Next-generation sequencing has been widely applied to understand the complexity of non-coding RNAs (ncRNAs) in the last decades. Here, we present CPSS 2.0, an updated version of CPSS 1.0 for small RNA sequencing data analysis, with the following improvements: (i) a substantial increase of supported species from 10 to 48; (ii) improved strategies applied to detect ncRNAs; (iii) more ncRNAs can be detected and profiled, such as lncRNA and circRNA; (iv) identification of differentially expressed ncRNAs among multiple samples; (v) enhanced visualization interface containing graphs and charts in detailed analysis results. The new version of CPSS is an efficient bioinformatics tool for users in non-coding RNA research.Availability and implementation
CPSS 2.0 is implemented in PHP?+?Perl?+?R and can be freely accessed at http://114.214.166.79/cpss2.0/.Contact
zyuanwei@ustc.edu.cn or qshi@ustc.edu.cn.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Wan C
PROVIDER: S-EPMC5860027 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data.
Bioinformatics (Oxford, England) 20171001 20
<h4>Summary</h4>Next-generation sequencing has been widely applied to understand the complexity of non-coding RNAs (ncRNAs) in the last decades. Here, we present CPSS 2.0, an updated version of CPSS 1.0 for small RNA sequencing data analysis, with the following improvements: (i) a substantial increase of supported species from 10 to 48; (ii) improved strategies applied to detect ncRNAs; (iii) more ncRNAs can be detected and profiled, such as lncRNA and circRNA; (iv) identification of differentia ...[more]