Ontology highlight
ABSTRACT:
SUBMITTER: Chevrette MG
PROVIDER: S-EPMC5860034 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Bioinformatics (Oxford, England) 20171001 20
<h4>Summary</h4>Nonribosomally synthesized peptides (NRPs) are natural products with widespread applications in medicine and biotechnology. Many algorithms have been developed to predict the substrate specificities of nonribosomal peptide synthetase adenylation (A) domains from DNA sequences, which enables prioritization and dereplication, and integration with other data types in discovery efforts. However, insufficient training data and a lack of clarity regarding prediction quality have impede ...[more]