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LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.

ABSTRACT: Summary:To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay. Availability and Implementation:R package LEAP available on CRAN. Contact:jun.li@nd.edu. Supplementary information:Supplementary data are available at Bioinformatics online.

SUBMITTER: Specht AT

PROVIDER: S-EPMC5860270 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.

Specht Alicia T AT Li Jun J

Bioinformatics (Oxford, England) 20170301 5

<h4>Summary</h4>To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay.<h4>Availability and implementation</h4>R package LEAP available on CRAN.<h4>Contact</h4>jun.li@nd.edu.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online. ...[more]

PMID: 27993778

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