Ontology highlight
ABSTRACT:
SUBMITTER: Sharma A
PROVIDER: S-EPMC5860643 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Sharma Anu A Laurenti Marcello C MC Dalla Man Chiara C Varghese Ron T RT Cobelli Claudio C Rizza Robert A RA Matveyenko Aleksey A Vella Adrian A
Diabetologia 20170527 8
<h4>Aims/hypothesis</h4>Shift-work is associated with circadian rhythm disruption and an increased risk of obesity and type 2 diabetes. We sought to determine the effect of rotational shift-work on glucose metabolism in humans.<h4>Methods</h4>We studied 12 otherwise healthy nurses performing rotational shift-work using a randomised crossover study design. On each occasion, participants underwent an isotope-labelled mixed meal test during a simulated day shift and a simulated night shift, enablin ...[more]