Ontology highlight
ABSTRACT:
SUBMITTER: Cubiles MD
PROVIDER: S-EPMC5861411 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Cubiles María D MD Barroso Sonia S Vaquero-Sedas María I MI Enguix Alicia A Aguilera Andrés A Vega-Palas Miguel A MA
Nucleic acids research 20180301 5
Although subtelomeric regions in humans are heterochromatic, the epigenetic nature of human telomeres remains controversial. This controversy might have been influenced by the confounding effect of subtelomeric regions and interstitial telomeric sequences (ITSs) on telomeric chromatin structure analyses. In addition, different human cell lines might carry diverse epigenetic marks at telomeres. We have developed a reliable procedure to study the chromatin structure of human telomeres independentl ...[more]