Ontology highlight
ABSTRACT:
SUBMITTER: Kim DJ
PROVIDER: S-EPMC5862242 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Kim Dong Joon DJ Lee Mee-Hyun MH Liu KangDong K Lim Do Young DY Roh Eunmiri E Chen Hanyong H Kim Sung-Hyun SH Shim Jung-Hyun JH Kim Myoung Ok MO Li Wenwen W Ma Fayang F Fredimoses Mangaladoss M Bode Ann M AM Dong Zigang Z
Carcinogenesis 20171001 11
Herbacetin is a flavonol compound that is found in plants such as flaxseed and ramose scouring rush herb, it possesses a strong antioxidant capacity, and exerts anticancer effects on colon and breast cancer. However, the effect of herbacetin on skin cancer has not been investigated. Herein, we identified herbacetin as a dual V-akt murine thymoma viral oncogene homolog (AKT) and ornithine decarboxylase (ODC) inhibitor, and illustrated its anticancer effects in vitro and in vivo against cutaneous ...[more]