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Simple fixed-effects inference for complex functional models.


ABSTRACT: We propose simple inferential approaches for the fixed effects in complex functional mixed effects models. We estimate the fixed effects under the independence of functional residuals assumption and then bootstrap independent units (e.g. subjects) to conduct inference on the fixed effects parameters. Simulations show excellent coverage probability of the confidence intervals and size of tests for the fixed effects model parameters. Methods are motivated by and applied to the Baltimore Longitudinal Study of Aging, though they are applicable to other studies that collect correlated functional data.

SUBMITTER: Park SY 

PROVIDER: S-EPMC5862370 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Simple fixed-effects inference for complex functional models.

Park So Young SY   Staicu Ana-Maria AM   Xiao Luo L   Crainiceanu Ciprian M CM  

Biostatistics (Oxford, England) 20180401 2


We propose simple inferential approaches for the fixed effects in complex functional mixed effects models. We estimate the fixed effects under the independence of functional residuals assumption and then bootstrap independent units (e.g. subjects) to conduct inference on the fixed effects parameters. Simulations show excellent coverage probability of the confidence intervals and size of tests for the fixed effects model parameters. Methods are motivated by and applied to the Baltimore Longitudin  ...[more]

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