Ontology highlight
ABSTRACT:
SUBMITTER: Zhang K
PROVIDER: S-EPMC5862521 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Zhang Kaiyi K Riba Ambre A Nietschke Monika M Torow Natalia N Repnik Urska U Pütz Andreas A Fulde Marcus M Dupont Aline A Hensel Michael M Hornef Mathias M
PLoS pathogens 20180309 3
Effector molecules translocated by the Salmonella pathogenicity island (SPI)1-encoded type 3 secretion system (T3SS) critically contribute to the pathogenesis of human Salmonella infection. They facilitate internalization by non-phagocytic enterocytes rendering the intestinal epithelium an entry site for infection. Their function in vivo has remained ill-defined due to the lack of a suitable animal model that allows visualization of intraepithelial Salmonella. Here, we took advantage of our nove ...[more]