Ontology highlight
ABSTRACT:
SUBMITTER: Dutton P
PROVIDER: S-EPMC5863794 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Statistical methods in medical research 20160901 5
Trials run in either rare diseases, such as rare cancers, or rare sub-populations of common diseases are challenging in terms of identifying, recruiting and treating sufficient patients in a sensible period. Treatments for rare diseases are often designed for other disease areas and then later proposed as possible treatments for the rare disease after initial phase I testing is complete. To ensure the trial is in the best interests of the patient participants, frequent interim analyses are neede ...[more]