Ontology highlight
ABSTRACT:
SUBMITTER: Bellon-Echeverria I
PROVIDER: S-EPMC5865166 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Bellón-Echeverría Itxaso I Carralot Jean-Philippe JP Del Rosario Andrea Araujo AA Kueng Stephanie S Mauser Harald H Schmid Georg G Thoma Ralf R Berger Imre I
Scientific reports 20180323 1
Protein-protein interactions (PPIs) are at the core of virtually all biological processes in cells. Consequently, targeting PPIs is emerging at the forefront of drug discovery. Cellular assays which closely recapitulate native conditions in vivo are instrumental to understand how small molecule drugs can modulate such interactions. We have integrated MultiBacMam, a baculovirus-based mammalian gene delivery tool we developed, with bimolecular fluorescence complementation (BiFC), giving rise to a ...[more]