Ontology highlight
ABSTRACT:
SUBMITTER: Menon A
PROVIDER: S-EPMC5866868 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Menon Alessandra A Creo Pasquale P Piccoli Marco M Bergante Sonia S Conforti Erika E Banfi Giuseppe G Randelli Pietro P Anastasia Luigi L
Stem cells international 20180311
Adult stem cell-based therapeutic approaches for tissue regeneration have been proposed for several years. However, adult stem cells are usually limited in number and difficult to be expanded in vitro, and they usually tend to quickly lose their potency with passages, as they differentiate and become senescent. Culturing stem cells under reduced oxygen tensions (below 21%) has been proposed as a tool to increase cell proliferation, but many studies reported opposite effects. In particular, cell ...[more]