Ontology highlight
ABSTRACT:
SUBMITTER: Cohen HC
PROVIDER: S-EPMC5866922 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Biomaterials 20150214
In the foreign body response, infiltrating PMNs exocytose granule subsets to influence subsequent downstream inflammatory and wound healing events. In previous studies, we found that PMNs cultured on poly(ethylene glycol) (PEG)-containing hydrogels (i.e., PEG and gelatin + PEG hydrogels) had enhanced primary granule release, yet similar tertiary granule release compared with PMNs cultured on polydimethylsiloxane or tissue culture polystyrene. PMN primary granules contain microbicidal proteins an ...[more]